Wednesday, March 26, 2008

2,6-diaryl pyridazinones with immunosuppressant activity


2,6-diaryl pyridazinones with immunosuppressant activity
Richard Arthur Norton (1958- ) on February 23, 1995

Abstract:
A class of 2,6-diarylpyridazinones of general structural formula I have been identified that exhibit exhibit immunosuppressant activity with human T-lymphocytes, and are useful as an immunosuppressants. [Structure] or a pharmaceutically acceptable salt, hydrate or crystal form thereof, wherein:
  • Patent number: 5506228
  • Filing date: Feb 23, 1995
  • Issue date: Apr 9, 1996
  • Inventors: Richard Norton, Mohammed K. A. Ibraham
  • Assignee: Merck & Co., Inc.
  • U.S. Classification: 514/247; 544/240
  • International Classification: A61K 3150